Informace o kvalifikační práci Účinek mutací v adipokinetickém hormonu a corazoninovém receptoru na metabolismus sacharidů a lipidů u <i>D. melanogaster</i>
In D. melanogaster, metabolic homeostasis is regulated by an interplay between insulin-like peptides and glucagon-like neuropeptides. Here we examined the influence of corazonin receptor (CrzR) mutations on levels of circulating saccharides, circulating lipids and starvation resistance. We also verified the interaction between null mutations of corazonin receptor and adipokinetic hormone and checked their influence on insulin signaling.
Klíčová slova
adipokinetický hormon, corazonin, inzulinu podobné peptidy, brummer
Klíčová slova v angličtině
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Rozsah průvodní práce
51
Jazyk
CZ
Anotace
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Anotace v angličtině
In D. melanogaster, metabolic homeostasis is regulated by an interplay between insulin-like peptides and glucagon-like neuropeptides. Here we examined the influence of corazonin receptor (CrzR) mutations on levels of circulating saccharides, circulating lipids and starvation resistance. We also verified the interaction between null mutations of corazonin receptor and adipokinetic hormone and checked their influence on insulin signaling.
Klíčová slova
adipokinetický hormon, corazonin, inzulinu podobné peptidy, brummer