The aim of this thesis was to create a fruit fly that is a mutant for multiple sirtuin genes, Sirt2,Sirt6 and Sirt7, by meiotic recombination and Crispr/Cas 9 technology. This fly would be used in order to achieve the creation of a fly mutant for all sirtuin genes, whose phenotype would be characterized by testing it under stress conditions.
Anotace v angličtině
The aim of this thesis was to create a fruit fly that is a mutant for multiple sirtuin genes, Sirt2,Sirt6 and Sirt7, by meiotic recombination and Crispr/Cas 9 technology. This fly would be used in order to achieve the creation of a fly mutant for all sirtuin genes, whose phenotype would be characterized by testing it under stress conditions.
Klíčová slova
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Klíčová slova v angličtině
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Rozsah průvodní práce
46 p. (50 410 characters)
Jazyk
AN
Anotace
The aim of this thesis was to create a fruit fly that is a mutant for multiple sirtuin genes, Sirt2,Sirt6 and Sirt7, by meiotic recombination and Crispr/Cas 9 technology. This fly would be used in order to achieve the creation of a fly mutant for all sirtuin genes, whose phenotype would be characterized by testing it under stress conditions.
Anotace v angličtině
The aim of this thesis was to create a fruit fly that is a mutant for multiple sirtuin genes, Sirt2,Sirt6 and Sirt7, by meiotic recombination and Crispr/Cas 9 technology. This fly would be used in order to achieve the creation of a fly mutant for all sirtuin genes, whose phenotype would be characterized by testing it under stress conditions.